In television advertisements, we are actively offering various enzyme preparations to improve digestion. If you re-eat, take an enzyme preparation. But is it all so simple? Is it possible to take enzymes regularly and haphazardly? First I want to draw your attention: although the advertisement says about improving the work of the stomach, in fact all enzyme preparations contain pancreatic enzymes. They do not work in the stomach, but are included in the digestive process at the next stage - in the duodenal ulcer. In television advertisements, we are actively offering various enzyme preparations to improve digestion. If you re-eat, take an enzyme preparation. But is it all so simple? Is it possible to take enzymes regularly and haphazardly?
First I want to draw your attention: although the advertisement says about improving the work of the stomach, in fact all enzyme preparations contain pancreatic enzymes. They do not work in the stomach, but are included in the digestive process at the next stage - in the duodenum. And the colored shell is designed to dissolve only in the duodenum.
Thus, enzyme preparations first of all facilitate the work of the pancreas. and only indirectly affect the stomach and partly - the liver.
It would seem, than bad, if we will facilitate the work of your digestive system? It turns out not so good. First, despite the fact that it is too expensive to obtain enzymes by chemical means, such preparations had animal origin only in the last century. Now enzymes are produced by biotechnology using transgenic microorganisms.
But the most important thing is not even this. If you “help” your muscles too much, they weaken (atrophy). Without physical exertion, the cardiovascular and respiratory systems also weaken, and the bones become more fragile. If it is not enough to train the brain, it also loses its activity. Not without reason, representatives of the intellectual professions preserve the memory and clarity of thinking much longer and better than others, even in old age.
Similarly, without the "training" and the digestive system weakens. Prolonged use of enzyme preparations leads to the emergence of the syndrome of a lazy pancreas. And these are not empty words: in chronic pancreatitis, after 20 years of illness, the mortality rate is up to 60% - and primarily because of the decrease in pancreas activity.
Therefore, although in the short term, the enzymes are quite safe, they should be used only if they cannot be dispensed with. In case of acute indigestion or exacerbation of a chronic disease (primarily pancreatitis), an enzyme preparation is necessary. However, it should be taken in a course of 1-2 months, simultaneously with a strict diet and comprehensive treatment of the disease as a whole. Fortunately, now there are a lot of herbal remedies, very effective for pancreatitis.
But it is extremely undesirable to take enzymes haphazardly. Of course, if you have eaten three to five times a year and have dealt with this problem with the help of tablets, there is no particular misfortune. But, unfortunately, any simple solutions lead to abuse.
The presence of enzymes on hand almost always means that a person will overeat regularly - every week or more. As a result, a drug will be needed in a year, then a stronger one, and then suddenly it will be revealed that without enzymes, even porridge cannot be digested.
Therefore, the most correct approach is to always control the quality and quantity of food eaten. In most cases it is very simple: you just have to eat in the cinema, as well as at home in front of the TV or with a book. If all attention is focused on food, the body will determine when it is time to stop.
The situation is more complicated on holidays, when interesting conversations, alcohol and changes in dishes dull the feeling of fullness. But holidays are not every day, and it is not so difficult to prepare for them.
First, half an hour before a meal, you need to drink 300-500 ml of water - plain or mineral. Most modern people are almost always in a state of minor dehydration. You may not feel thirsty, but your stomach, pancreas and liver will be very grateful for a sip of water before hard work.
Take a vegetable hepatoprotector shortly before the holiday. Do not be lazy to go to him in the pharmacy. Also consult with a pharmacist - they probably have several herbal preparations that improve the work of the stomach and digestion in general. These two or three natural medicines will not hurt to take before the holiday, and several times after it.
To help the stomach and pancreas, it is not necessary to take enzymes in pills. Pineapples, kiwi and papaya contain very strong proteolytic enzymes that perfectly improve digestion.
If the mistress of the holiday you - be sure to serve at least one of these fruits. First of all, they are relevant to meat and fish dishes, as they contribute to the digestion of proteins.
If you go to visit - no one bothers to bring a basket of kiwi or pineapple with you. I think you will not be so difficult to convince the hostess to serve fruit to the table, not waiting for dessert.
Of course, the best remedy for overeating is not to eat too much. But when you are at the holiday table, it can be very difficult to resist. And in such cases, natural remedies should come to the rescue - and first of all, this is the correct selection of fruits in the menu. And drugs are better to postpone in case of illness. And let them you never need.
What are enzymes and why are they needed?
Only relatively small molecules are able to penetrate the blood through the intestinal wall: amino acids, monosaccharides (glucose, fructose), fatty acids. All this - the elementary "bricks" of more complex substances: proteins, fats and carbohydrates. Enzymes break down complex substances into simple "bricks":
- amylase - complex carbohydrates,
- lipases - fats,
- proteases - proteins.
Digestion, that is, the splitting of complex substances into simple ones, begins in the mouth, where saliva amylase is activated. In the stomach, where the medium is acidic, the activity of amylase is suspended, the food is processed by the proteolytic enzyme pepsin, which can only work in an acidic environment. At the exit from the stomach (in the antrum) the acidic environment of the food is neutralized, and the food lump passes into the duodenum - the initial section of the small intestine. Here it is processed by bile, which emulsifies fat - turns it into a suspension of the smallest droplets. So the area of contact of fats with lipases increases. In addition to lipases, amylases and proteases work in the duodenum. This complex of enzymes is produced by the pancreas, so its analogue contained in drugs is called pancreatin (lat.pancreas - pancreas).
If for some reason the enzymes are not produced enough or they cannot be active (for example, the proteins in the stomach do not break down when the acidity of the gastric juice is reduced), the digestion process is disturbed. Not fully processed food components begin to irritate the intestinal walls, causing diarrhea, pain, bloating. After half an hour - an hour after eating, there is a sharp urge to go to the toilet, the excreted feces become abundant, foamy, have a sharp unpleasant odor.
Often, this problem occurs in chronic pancreatitis, when cells that produce enzymes die under the influence of inflammation. Another common cause is disruption of the normal flow of bile due to biliary dyskinesia or after removal of the gallbladder. Not enough emulsified fat is less in contact with enzymes and worse splits.
Top Digestion Enzymes Rating
|Nomination||a place||Name of product||price|
|The best enzymes for adults||1||Mikrasim||635 ₽|
|The best enzymes for children||1||Kolif drops for children||1 573 ₽|
|2||Creon Micro 5000||1 224 ₽|
|THE BEST VEGAN ENZYMES||1||Now Foods, Plant Enzymes||1750 ₽|
|3||Vegan enzymes||390 ₽|
The best enzymes for adults
In this ranking group, we collected the most popular digestive enzymes suitable for adults.
The pancreatic enzyme complex - pancreatin - containing amylases, lipases and proteases, is placed in microspheres, which, in turn, are packed in capsules. The capsule dissolves in the stomach, the microspheres are evenly mixed with the food lump, passing into the intestine and already there dissolve under the action of an alkaline medium, releasing enzymes. Thus, the enzymes are evenly mixed with food and act as efficiently as possible.
Clinical recommendations for the treatment of exocrine pancreatic insufficiency separately stipulate that microspheres or microtablets, which are activated only in the lumen of the small intestine, are the only effective form of supplying enzymes to the intestine.
Take the capsule three times a day with meals. Considering the form of drug release, the capsules cannot be chewed - if the shell of the microspheres is damaged, the enzymes are inactivated in the acidic environment of the stomach.
If the drug is used occasionally with overeating, a dosage of 10,000 IU is sufficient. In other cases, the means must be prescribed by the doctor, he will determine the required dose.
Possible analogues are Hermital, Creon.
- high price.
Economy option: all the same extract of the pancreas of animals - Pancreatin, as in the previous tool, but placed in tablets with an enteric-coated shell. Enzymes are not inactivated in the stomach, they begin to act only when they enter the intestine, but given that the tablet needs time to dissolve, it is more difficult to talk about the effective interaction of enzymes with food (as we remember, the activity of enzymes is higher, the higher their area of contact with food suspension ).
However, given the fivefold difference in price with the previous medicine from our rating, it is not surprising that the drug has many fans. Nevertheless, we would recommend it primarily to healthy people, whose quality of life is not too dependent on the effectiveness of the medication taken.
Possible analogues - Penzital.
Pancreatic enzymes and digestion
The pancreas is the main organ in the digestive system. The ducts of this organ pass into the duodenum, which is the initial section of the small intestine. These ducts transport pancreatic enzymes to the area of digestion, where proteins, fats and carbohydrates are broken down.
The exocrine part of the pancreas produces:
- Bicarbonates, which create an alkaline environment in the duodenum to neutralize the hydrochloric acid secreted by the stomach,
- Electrolytes and water,
- Enzymes for digestion.
Pancreatic enzymes in turn can be divided into:
Lipazuwhich participates in the breakdown of fats to fatty acids and glycerol. It helps to improve the absorption into the blood of substances entering the stomach.
Amylasewhich is involved in the breakdown of starches to oligosaccharides. Further, other digestive enzymes break down the resulting substance to glucose, which is necessary to replenish energy. Glucose enters the body by absorption into the blood.
Proteaseswhich in turn are divided into pepsins and chymotrypsins, carboxypeptidase, elastase. Pepsins and chymotrypsins are involved in the breakdown of proteins into peptides. Then carboxypeptidase processes peptides to the amino acid, which is favorably absorbed by the body. Elastase enzymes break down elastin and other types of protein.
The secretion of enzymes in the digestive system occurs through interconnection. With increasing levels of chymotrypsin and trypsin in the duodenum, the production of enzymes is suspended. The selection is resumed after a peculiar signal is received in the form of stretching the intestinal walls, the appearance of odor and taste.
Digestive enzymes and their features in pancreatitis
As you know, all human organs are composed of tissues, which in turn are formed from proteins. The pancreas is no exception. Meanwhile, the body has a special protective function, due to which the produced enzymes are not able to digest the body itself. This is due to the fact that enzymes begin their activity only after they are in the lumen of the small intestine.
Pancreatitis is a serious disease of the pancreas, which is quite common in humans. The peculiarity of this disease lies in the fact that pancreatitis pre-activates enzymes ahead of time, which leads to the rapid destruction of not only incoming food, but also of the internal organ itself, which secretes these enzymes.
The pancreas includes proteins that, under the influence of enzymes, begin to break down, leading to the death of pancreatic tissue. In the case of acute pancreatitis, this process occurs very quickly. If you do not immediately take the necessary measures and do not seek medical attention, a person may die. Chronic pancreatitis delays the process of destruction for a long time, the disease develops gradually.
Pancreas and its failure
The pancreas secretes enzymes in the intestinal area and blood vessels, so there is a lack of external or internal secretion. In case of insufficiency of internal secretion, diabetes mellitus most often develops in a person. In this case, the pancreas does not cope with the full production of insulin, which in turn is responsible for the absorption of sugar in the cells of the organs. The disease can be detected by the results of blood tests, which will show an increased level of glucose in the blood.
In case of insufficiency of external secretion, the number of enzymes produced by the digestive system decreases. This leads to the fact that the patient is not able to eat food in large quantities. Because of the disruption of the pancreas, enzymes do not cope with the splitting of triglycerides. This leads to the fact that after eating fatty foods a person feels a feeling of nausea and pain in the abdomen.
Pancreatic insufficiency can be functional and organic. In the first case, the disease is temporary and is cured fairly quickly after the patient begins to take the necessary medication prescribed by the doctor.
This type of illness can be caused by any type of poisoning or infectious disease. With organic insufficiency of the pancreas, the disease is so neglected that it cannot be treated quickly. In this case, it is very difficult to get rid of pancreatitis and restore full-fledged organ function.
For the treatment of the disease the patient is prescribed a strict medical diet, which excludes the ingestion of fatty foods, or the menu of the fifth table. Nutrition occurs five times a day in small doses.Additionally, to improve the functioning of the pancreas is assigned to receive enzymes. Such drugs are available in pill form, they are usually taken at the time of meals so that the medicine is well absorbed and the patient does not feel nauseous.
Preparations for the treatment of pancreas
Enzyme preparations help to fill the missing level of important enzymes in the body, if the pancreas is not able to independently produce the necessary quantity of them due to the disease. However, it is important to understand that this does not help to restore the functioning of the pancreas.
Depending on the severity of the disease, the doctor prescribes the required dose of medication and tablets for pancreatitis. With mild deficiency in old age, it is recommended to take small amounts of enzyme preparations. If the work of the pancreas is not restored, the doctor prescribes a daily medication.
Enzyme preparations are made from the tissues of animal organs. You can buy them at any pharmacy without a doctor's prescription. These drugs include
Dosed drugs according to the level of lipase, which is involved in the process of digesting fat. It is this substance that is usually lacking in the splitting of triglycerides. To ensure that enzymes do not break down when they fall into the gastric juice, the preparations are coated with a special coating.
As a result, the tablet activates the action of enzymes only after it enters the duodenum. In addition to tablets, drugs are also available in capsule form. This type of drugs affects the body more effectively due to the fact that they mix well with food and quickly enter the body.
If all other means of our rating are created in order to support the functioning of the small intestine, this preparation contains a complex of enzymes to improve digestion in the stomach.
As already mentioned, this is where the first stage of protein digestion occurs. But in order for gastric proteases to work, an acidic environment is necessary. With atrophic gastritis due to prolonged inflammation, the glands that produce both enzymes and gastric juice die. There is a lack of digestion in the stomach with heaviness after eating, rapid saturability, and belching with air. Frequent and manifestations of dumping syndrome caused by hitting a large amount of insufficiently processed food in the intestine:
- sudden weakness after eating, until fainting,
In such a situation, the doctor may prescribe Acidin-pepsin.
Contains a complex of gastric enzymes (pepsin) and betaine hydrochloride. Pepsin is an extract from the mucous membrane of the pig stomach. Betaine hydrochloride, getting into the water, hydrolyzes (decomposes) with the release of hydrochloric acid, providing an optimal environment for the action of pepsin.
Two tablets need to be dissolved in half a glass of water and drink during a meal.
The best enzymes for children
Medicines for children have their own characteristics. Firstly, it is forbidden to give tablets to children under 3 years old, and capsules up to 5 years old, it is believed that only at this age a child is able to swallow the medicine without choking. Children do not like to drink pills. And if, say, for the antipyretic, you can use the "grandmother's" method, stirring the crushed medicine into jam, with enzymes for digestion, such a method of circulation is unacceptable - because if the shell of the tablet with pancreatic enzymes collapses in the stomach, the active ingredient will lose its activity.
Moreover, for children it is not the problems with the pancreas that are more relevant, but the lack of a single enzyme - lactase - without which the baby is unable to properly digest the disaccharide contained in milk - lactose.
This is manifested by a sharp abdominal distension, bubbling, colic, frequent abundant stools. And if an adult who does not tolerate milk can simply not drink it, then the child, especially the breast one, will not do without milk. Of course, there are lactose-free mixtures, but they are still not breast milk, and they are not cheap. That is why we start ranking the best enzymes for children with a drug containing lactase.
Kolif drops for children
This is a dietary supplement recommended for children suffering from lactase deficiency. Available in a bottle with a dropper. 1 dose of the drug - 4 drops. Before you feed the baby, you need to strain 2 to 3 teaspoons of milk, stir the medicine in them, give the baby to the spoon and continue to give the breast as usual. To the baby who is on artificial feeding, 4 drops of drug are parted on all volume of the mix intended for one feeding.
The medicine and the milk diluted with it cannot be frozen or heated above 37 degrees.
As a rule, by half a year in children suffering from lactase deficiency, the production of its own enzyme is getting better. therefore, by this age one can smoothly reduce the amount of money. But sometimes the problem remains for life.
Do you need digestive enzymes?
If you make it a rule to regularly monitor the health of your stomach and digestive tract, then you can immediately find out about any changes. The sooner you find the source of the problem, the easier and faster you can solve it. There are a number of signs that many do not pay attention, indicating the presence of problems with the stomach:
- Drowsiness. If you sleep for 6-8 hours a day, but still go sleepy, then, most likely, your body does not receive important vitamins, trace elements and minerals. To replace them, he is forced to use energy reserves, which results in a drowsy state.
- Fatigue. The cause of chronic fatigue can also be a deficiency of nutrients in the body.
- Deterioration of the skin. It becomes lethargic, loses its elasticity and attractive appearance.
- Stomach ache. If the pain in the abdomen increased, then this is a clear sign of a violation of the digestive system. Even if the pain is weak and easily tolerated.
- The deterioration of the nails and hair. One of the most common and important factors indicating serious stomach problems.
- Intestinal disorders. Regular constipation, diarrhea, flatulence and bloating.
- Weakened appetite. Unpleasant sensations in the stomach directly affect a person's desire to eat. If you began to eat sharply 1-2 times a day, instead of the usual 3-4, then the digestive system is experiencing some difficulties.
One of the 7 factors presented is enough to immediately visit a qualified specialist and start taking enzyme preparations for digestion.
Indications for use
Enzymes are secreted by external secretion glands. In each of the stages of digestion, which begins in the mouth, enzymes are involved. The main indication for the appointment of these drugs is enzyme deficiency. This happens with the following diseases:
- Inflammatory diseases of the digestive tract organs: gastritis, pancreatitis, cholecystitis, hepatitis, cholangitis, colitis.
- Autoimmune bowel disease: Crohn's disease, ulcerative colitis.
- Irritable bowel syndrome, functional dyspepsia.
- Congenital fermentopathies: lactase deficiency, cystic fibrosis, celiac disease.
- Diseases of the teeth leading to poor chewing of food.
- Patients after surgery with general anesthesia enzymes can be appointed for the period of recovery of bowel function.
- Enzymes are necessary as replacement therapy for individuals after resection of the stomach, pancreas, removal of the gallbladder.
Also, drugs may be needed for people who take anti-inflammatory and antibacterial drugs for a long time, as well as hormones and cytostatics.
Recommended: To avoid the development of enzyme deficiency, use only well-prepared products, eat often and in small portions, diversify your diet with dairy products, fruits, vegetables, cereals.
How is enzyme deficiency manifested?
The lack of enzymes begins to manifest itself with symptoms of digestive disorders: heartburn, heaviness in the stomach, belching, increased gas formation. Due to impaired absorption and absorption of useful substances, problems with skin, nails and hair appear, the general condition is disturbed. A person lacks vitamins and minerals, there is fatigue, drowsiness, reduced performance.
Interesting: Enzyme preparations can be prescribed as a component of complex therapy in dermatology, gastroenterology, allergology and other areas of medicine.
Some patients, knowing about the problems with digestion, use these drugs periodically, before the feast. This is not correct, as overeating in combination with the uncontrolled use of enzymes disrupts the function of the digestive tract and leads to its consequences. Therefore, enzyme preparations should be prescribed by a specialist and taken reasonably, and not in cases where a person cannot control his appetite.
Drug Types with Enzymes
Enzyme preparations are derived from the pancreas of pigs, the pancreas of cattle and plants. Preparations can be either purely animal or vegetable origin, or combined. In appointing a particular remedy, the physician is guided by its main enzyme components:
- Pepsin - an enzyme of the gastric mucosa,
- Pancreatic enzymes - lipase, amylase and trypsin - derived from the pancreas of pigs or cattle,
- Remedies with bile acids,
- Enzymes of plant origin,
- Enzyme preparations that break down lactose (used for lactase deficiency),
- Combined drugs.
Important: All enzyme preparations begin to act no earlier than 20 minutes after ingestion, therefore it is recommended to use them immediately before a meal.
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Pepsin is an enzyme secreted by the gastric mucosa. It is necessary for the breakdown of proteins. Pepsin preparations, namely Pepsin, Abomin and Pepsidal, are used in people with diseases of the stomach, most often in atrophic gastritis.
Proteins are important components of energy metabolism, and with insufficient production of pepsin weakness and anemia develop. In addition, food from the stomach enters the intestine is not sufficiently processed, which requires intensive work from the gastrointestinal tract and can cause intestinal function disorders. Enzyme preparations containing pepsin are prescribed to patients as lifelong replacement therapy after gastrectomy.
Creon, Mezim-forte, Pancreatin - all these are digestion pills with the same active ingredient - Pancreatin. The active ingredient of the drug is enclosed in granules, which are coated with a protective sheath. Pancreatin is an enzyme of the pancreas that acts in the small intestine, therefore, the protective sheath allows you to deliver the active substance exactly to the target.
There are many indications for using the remedy, but since pancreatin replaces the natural pancreatic enzymes, it is prescribed medication mainly in the pathologies of this organ. Pancreatic enzymes are safe and can be used for a long time if necessary. For example, in chronic pancreatitis and after resection (removal of a part) of the pancreas, Creon, Pancreatin, or Mezim-forte may be recommended before each meal as a replacement therapy.
Important: If the doctor recommended to drink enzymes constantly, then it should be obeyed, in order not to disturb the pancreas function even more. An alternative to this can serve as a strict diet for an indefinite period.
Bile Acid Remedies
Bile acids are involved in the breakdown of fats and stimulate the secretory activity of the pancreas. Also in the composition of these drugs include plant fiber, stimulating peristalsis, and defoamers, eliminating meteorism. The indications for use are diseases of the liver and gallbladder, in which the production of bile is disturbed. The preparations with bile acids include Festal, Digestal and Enzistal.
In addition to bile acids, these drugs also contain pancreatic pancreatic enzyme. Therefore, they can be taken in the pathologies of the pancreas. However, agents with bile acids are not always interchangeable with Pancreatin (Mezim), because patients are often allergic to components of bile. Therefore, these drugs are used only in individuals with impaired liver function.
Enzymes to improve the digestion of plant origin have a complex effect on the gastrointestinal tract. They improve the motility of the stomach and intestines, reduce gas formation, improve the absorption of beneficial elements, stimulate the metabolism and normalize the breakdown of fats, proteins and carbohydrates.
Medicines can be used for diseases of the liver, pancreas, small and large intestines, as well as for the normalization of digestion in the postoperative period.
Despite the diverse effects, these drugs are rarely prescribed, as there are more effective herbal enzyme preparations. Most often, enzyme preparations of plant origin are prescribed before preparing for the study of the digestive tract.
Such means include Pepfiz, Unienzim, Solizim, Oraza, Sestal. Many enzyme preparations of plant origin, in particular, pepfiz, are contraindicated in children and pregnant women.
Enzyme preparations that break down lactose
Lactase deficiency is not uncommon today. Patients suffer from problems with digestion, they treat skin and hair diseases, not knowing that a lack of lactose is the cause of everything. This problem can be solved simply - eliminate milk, cream, cheeses from the diet. However, when lactase deficiency is detected in infants who are breastfed, it is not so easy to find a way out.
Lactose-free mixtures are expensive and do not allow the child to receive those nutrients that are in mother's milk. To this end, preparations with enzymes for children that break down lactose have been created. A woman needs to express milk, add a few drops of medication to it and the child will be safe. Such drugs include drugs Lactraz, Laktayd, Kerulak. These drugs can also be used by adults.
Interesting: In case of lactase deficiency, dairy products are not contraindicated, therefore, people with this enzyme can get all the nutrients from kefir, curd and other dairy products.
Wobenzym - the main representative. Contains plant and animal enzymes. The drug not only replaces enzyme deficiency, but also has anti-inflammatory, anti-edematous, fibrinolytic and analgesic effects. Due to this, Wobenzym is an excellent tool in the treatment of autoimmune bowel disease (Crohn's disease and ulcerative colitis).
The tool is actively used in rheumatology, traumatology, endocrinology, dermatology and other areas of medicine.Despite the lack of a specific action, the drug has excellent results, has virtually no side effects and can be used for a long time, for 1 month or more.
Medicines for children and pregnant women
Enzyme preparations to improve digestion have practically no contraindications except for hypersensitivity to the components of the drug, therefore many of them are approved for use by children. However, it is impossible to give a medicine to a child on its own, since depending on the age and body weight, the dose and the course of taking the drug vary. Especially carefully drugs are prescribed to children up to 3 years.
Children are most often prescribed drugs Abomin, Mezim-forte, Pancreatin and Creon, selected depending on the state.
Important: Pancreatic preparations (containing pancreatin) cannot be used for acute pancreatitis and exacerbation of chronic inflammation.
In pregnant women, due to physiological changes in the body, signs of indigestion may be observed. Heartburn, flatulence, abdominal pain, constipation and diarrhea - all of these manifestations serve as symptoms of enzyme deficiency. Best of all, a special diet can help eliminate them, but sometimes a gynecologist can prescribe enzymes.
Also, tools for improving digestion during pregnancy may be needed for women with chronic pancreatitis. The gynecologist selects the variant of the medicine and its dose together with the therapist or surgeon who drives the patient.
Recommended: In the first trimester, the most important organs of the baby are laid down, therefore the number of medicines consumed by a woman should be minimized. Taking any medication without consulting a gynecologist is prohibited. How, then, to improve digestion? Diet and eat often in small portions.
Looking at the variety of enzyme preparations, patients should understand that one drug is not always an analogue of another, and not every medicine works effectively in various diseases. Therefore, only a reasonable prescription medication by the attending physician will help to cope with enzyme deficiency.
Among the multitude of drugs the leading drugs for digestion. They are indeed present in almost every first-aid kit. In medicine, they are called enzyme preparations to improve digestion. For the assimilation and processing of food substances contained in drugs, the body is produced independently. However, there are cases when the synthesis of enzymes occurs in insufficient volume. This leads to bloating, increased flatulence, and heaviness in the stomach. And then it is necessary to take enzyme preparations to improve digestion.
Common causes of violation
Today, the regulation of digestion is necessary for many people. The reasons for the violation of the process may lie in both diseases and in the wrong diet. Doctors identified the main sources that affect the deterioration of digestion:
- Insufficient food processing. The use of raw fish, not roasted meat, sliced.
- Binge eating. Excessive amount of food can not be fully processed by those enzymes that the body secretes.
- Monotonous food. If a person uses only one type of nutrients (for example, sweets-carbohydrates or kebabs-proteins), then there is a lack of necessary enzymes.
- Bad chewing. This pattern can be observed in the case of diseased teeth or unsuccessful prosthetics. The process of splitting food begins in the oral cavity. Therefore, poor chewing initially worsens the process of digesting food.
- Inflammatory diseases of the digestive tract. The formation of enzymes in duodenitis, gastritis, colitis, chronic pancreatitis, cholecystitis, hepatitis, cholangitis is noticeably reduced. As a result of such pathologies, the formation of substances necessary for the digestion of food is disturbed - bile, hydrochloric acid. Patients are necessarily shown regulation of digestion with the help of enzyme preparations.
- Irritable bowel syndrome, diarrhea. In these diseases, the speed of movement of food masses along the path is violated. As a result of this pathology, the enzymes simply do not have time to act on food.
- Fermentopathy. This disease (acquired or congenital) is characterized by an enzyme deficiency. This clinic is typical for the following pathologies: lactase deficiency, celiac disease, cystic fibrosis.
- Use of medications that can disrupt the intestinal microflora. The use of NSAIDs, cytostatics, antibiotics (especially in the case of long-term treatment) adversely affects the functioning of the digestive tract.
- Surgical intervention. Unpleasant symptoms may occur after cholecystectomy, resection of the stomach, colon or small intestine.
- Pregnancy. The developing fetus can squeeze the digestive organs.
There are many enzyme drugs on the pharmacological market. Among them are:
- Herbal preparations - “Wobenzym”, “Unianzyme”, “Oraza”, “Pepfiz”.
- Medicines made from pancreatic pigs - Mezim Forte, Pancreatin, Creon, Lycreatis, Penzital.
- Medicines obtained from the gland of large horned animals - Digestal, Festal, Enzistal.
In medicine, enzyme preparations are divided by origin and composition. The classification includes the following groups.
Agents containing pancreatin, components of bile, hemicellulose
We list the enzyme preparations to improve digestion included in this group:
Bile acids stimulate the secretion of the pancreas, improve intestinal motility, gall bladder. They provide emulsification of fat in the body and contribute to the increase in cholerosis. Plant fiber improves intestinal motility. Simethicone, Dimethicone - the components included in this medicine are defoamers that perfectly relieve meteorism.
Why can the process of digestion be disturbed?
In order to successfully cure the consequences, it is necessary to establish the cause of the disease correctly. The stomach is a fairly sensitive organ, many factors can affect its work. Highlight the most popular:
Unhealthy food. Smoked, salted and fatty foods make the stomach work at full strength. If there is a lot of such food, then violations occur during the digestion process.
Eating large amounts of food. Even if your diet consists solely of healthy foods, you need to know the measure. Experts advise you not to eat up to faintness and leave the dining table slightly hungry. The connection between the stomach and the brain is not lightning, so sometimes it seems that you want to eat more, while the body has already received a sufficient amount of food.
Inadequate chewing food. Whole foods are digested much more slowly and more difficult. Chew your food thoroughly and try not to eat in a hurry.
Late meals. Each person has a different wakefulness schedule, so the rule “do not eat after 9 pm” is not always correct. It would be more logical to say: “Do the last meal 3–4 hours before bedtime.”
Drinking water in parallel with food. Most people know that a person needs to drink about 2-3 liters of water per day. This truth is not questioned, but there is one clarification. Water should be drunk 30 minutes before or 10-15 minutes after eating. During the meal is strictly not recommended to drink water. It destroys the digestive enzymes, which complicates the process of digestion.
For many of these reasons, people do not pay attention until their digestive system fails. It is enough to follow simple rules to protect yourself from unpleasant consequences.
Enzyme preparations for digestion - a list
In the event of serious problems with the stomach, it is necessary to review the diet and purchase digestive enzymes. They are divided into several subgroups, which are aimed at combating diseases of different nature. There are 3 main subgroups of digestive enzymes:
- Drugs whose composition is based on pancreatin. Pancreatin is the main digestive enzyme that, in a short period of time, eliminates all stomach problems. This subgroup includes the following list of drugs - Pancreatin, Mezim, Creon, Penzital.
- Preparations whose composition is filled with various elements (hemicellulose, bovine bile powder, pancreatin, etc.) that help to cope with digestive disorders, the process of splitting fats and the production of pancreatic enzymes. This subgroup includes the following list of drugs - Festal, Enzistal, Panzinorm.
- Drugs whose composition is filled with microelements that help normalize the work of the exocrine function of the pancreas. This subgroup includes the following list of drugs - Somilaz, Oraz, Negidaz.
Important! Only an experienced doctor will be able to determine which drug and from which subgroup will help to deal with your problem. Self-medication often leads to deterioration.
In addition to the active substance, its form of release also affects the effect of the drug. In modern pharmacology, enzyme preparations can be found to improve digestion in the form of tablets or capsules. The lack of pills is that when they enter the stomach, they completely dissolve there. While the capsules have several layers of the shell, which allow the active substance to be transported both to the stomach and to the intestine. Thus, it is more expedient to acquire some drugs in the form of capsules, especially if their action is designed for the intestines.
Let us consider in more detail the most effective and popular drugs.
The drug has the same name with the main digestive enzyme, which indicates its high efficiency. To resort to the use of drugs should be when:
- reducing pancreatic enzyme production,
- serious diseases of the intestines, stomach, liver,
- eating too much food
- low-active lifestyle,
- disorders of the chewing process.
There are no generally accepted dosages for the drug: some take one tablet per day, some take two. It is advised to follow the recommendations of the doctor who will prescribe the dosages that are optimal in your situation.
Side effects are mild and rarely occur. Among the most common side effects are:
- discomfort in the abdomen,
- allergic processes (rash, redness, etc.),
- increase in the amount of uric acid.
This drug is very popular because it comes in capsules. As noted earlier, capsules have a complex effect on the stomach and intestines, which significantly increases the effectiveness of treatment. The active ingredient of the drug is pancreatin. Creon is prescribed for:
- chronic pancreatitis,
- postoperative therapies
- cystic fibrosis,
- malignant tumors growing near the stomach,
- bulk meals (holidays, birthdays, etc.).
The optimal dosage is 1 capsule before each use of food. It is advisable not to crack the capsule, otherwise the active substance will dissolve in the stomach and will not enter the intestine.
The drug has no side effects. Occasionally, there are disorders in the gastrointestinal tract in the form of diarrhea or pain. Similar reactions occur due to additional elements of the drug.
Important! Creon is considered a powerful drug, so be sure to consult your doctor before taking it.
A more well-known drug, as in its time was carried out an extensive advertising campaign. One tablet contains pancreatin, amylase, lipase and protease. A set of components similar to the drug Pancreatin. Mezim is accepted when:
- pancreatic enzyme production is reduced,
- there is constipation
- there are inflammatory processes in the stomach,
- inflammation of the pancreas is formed.
The dosage is prescribed by the attending physician. Most often it is 1 tablet before each meal. Depending on the nature and degree of neglect of the disease, the course can last from 2-3 days to 4-6 months.
The drug is contraindicated in people suffering from intestinal obstruction, jaundice or hepatitis.
Mezim is a more expensive analogue of Pancreatin. The main difference is taste. The outer layer of the pill Mezim is much more pleasant to taste, so it is often bought for children.
In addition to pancreatin, Festal contains hemicellulose and bovine bile extract. Hemicellulose takes an active part in the processes of cellulose degradation, and bovine bile extract normalizes the absorption of fats and vitamins. With these elements, Festal has a quick effect on the digestive system.
The drug is taken with:
- violations of the secretion of pancreatic enzymes,
- abdominal distention,
- bowel irritation,
Due to the large number of different components, Festal has a wide list of contraindications. The drug is not recommended for use in the following diseases:
- allergic to the elements that make up
- intestinal obstruction
- diabetes mellitus (due to the content of sucrose and glucose in the tablet shell).
An effective drug that solves problems with the digestive tract. Like Festal, Enzistal includes hemicellulose, pancreatin and elements of bile. Additional ingredients harmoniously interact and enhance the overall result. Enzistal take with the following symptoms:
- deficiency of enzymes of the digestive system,
- exacerbated flatulence,
- violations of chewing processes,
- inactive lifestyle.
If a person suffers from renal or hepatic failure, it is recommended to limit the use of Enzistal. The attending physician should adjust the frequency and volume of dosages so as not to cause complications of existing diseases.
Side effects of the drug:
- discomfort in the stomach,
- the appearance of irritation on the mucous membrane,
It is urgent to stop taking Enzistal, if at least one of the side effects is manifested.
The active substance of the drug belongs to a subgroup of digestive enzymes that affect the exocrine function of the pancreas. The mechanism of action is fundamentally different from all previous drugs. The elements of the drug break down fats and transform them into missing enzymes.
Somilase course is recommended for:
- deficiency of digestive enzymes
- chronic pancreatitis,
- developing gastritis,
- inflammatory processes in the intestines,
- diseases of the liver and gall bladder,
- the passage of postoperative therapy.
Somilase has no contraindications, except for allergic reactions to certain elements of the composition. The drug is easily tolerated and effectively solves the existing problems with digestion.
Important! The drug strongly stimulates the pancreas, so before taking should consult a doctor.
Preparations based on digestive enzymes play an important role in the life of every person. Especially those who do not follow their diet and do not follow the rules written above.
The presented remedies will help you get rid of the discomfort and disturbances in the digestive system. You can also take them as a prophylaxis.But remember that their action makes serious adjustments to the functioning of the body, so you must always consult a doctor.
This drug is prescribed for disorders of the digestive functions, reducing the acidity of gastric juice, gastroenteritis, enterocolitis, gastritis.
However, one should not forget that the active ingredient of the drug is rennet. Therefore, when it is intolerable, the drug is contraindicated. This remedy does not apply in the case of regurgitation syndrome, vomiting in babies at an early age. Sometimes the medication can cause temporary nausea, heartburn. The tool is allowed to use children. Children from 1 year old can be taken to therapy with the drug "Abomin".
The price of this tool is about 171 rubles.
This tool helps to compensate for the lack of pancreatic enzymes. It stimulates the digestion of food. Often, the medication is prescribed for chronic pancreatitis, ulcers, enteritis, gastritis, dysbacteriosis, and intestinal infections. Sometimes it can be taken sporadically to facilitate the digestion process.
The drug "Mezim" categorically contraindicated in acute exacerbation of pancreatitis. During the reception of this tool may be mild nausea, sometimes vomiting. In some patients (rarely), the drug can provoke atopic dermatitis, urticaria, angioedema, anaphylactic shock.
This tool can be used for children. Prescribed medication individually, given the severity of the pathology.
This medicine is quite effective in violation of digestion. It is recommended to use it if the patient feels a feeling of fullness in the stomach during overeating, abuses fatty or unusual food. CREON is an excellent replacement therapy for pancreatic insufficiency. Often it is used to prepare the patient for research of organs in the stomach. In acute pancreatitis, the drug is not used.
This drug has virtually no contraindications. It is suitable for pregnant women and babies. However, in the latter, in some cases, the drug may cause constipation.
The medicine "Pancreatinum 8000"
This is an excellent enzyme preparation that facilitates the digestion of carbohydrates, fats, proteins. It promotes their absorption in the small intestine. One tablet of the drug "Pancreatin 8000" contains the necessary enzymes in international units:
- lipase - 8000,
- amylase - 5600,
- protease 370.
The tool is in demand for pathologies of the pancreas, chronic inflammatory and dystrophic diseases of the stomach, liver, intestines, gall bladder. The drug can be used by patients and with the normal functioning of the gastrointestinal tract with errors in diet, physical inactivity.
The drug is prohibited to use in case of exacerbation of pancreatitis or hypersensitivity to the drug.
In the process of drug therapy of chronic pancreatitis, as a rule, a complex of drugs is prescribed. At the same time, the actions of analgesics, antispasmodics and choliner preparations are combined, H2-blockers and antacids, antienzyme and enzyme agents are also shown.
In inflammatory processes, drugs such as No-shpa, Papaverin, Platyphyllin, Atropine are usually prescribed. These drugs for the pancreas are taken orally or in the form of subcutaneous injections (for acute pain, for example). Against the background of exacerbation of chronic pancreatitis, exocrine organ insufficiency is of particular importance. In this regard, enzyme preparations, H2-blockers and antacids are recommended.
Among the latter, it should be noted such medicines as "Phosphalugel", Almagel "and other alkaline mixtures of the liquid substance. H2 blockers are used to relieve severe pain. Such drugs as femotidin, ranitidine and others are prescribed, for example.
Some medications are prescribed to patients for a long time. Therapy does not do without enzyme preparations. Recommended, in particular, such agents as amylase, lipase, trypsin. These drugs are used to restore the pancreas. Their action is aimed at suppressing pancreatic secretion. As a rule, enzyme means prescribed immediately after the removal of an acute attack, accompanied by pain. The effectiveness of these drugs is manifested in the weakening of dyspepsia. This, in turn, is expressed in stabilizing the mass and stopping diarrhea. As practice shows, the exacerbation of the condition is removed within three to five weeks from the beginning of the use of funds. Complete elimination of acute pancreatitis is noted after six months or a year. Among the enzyme drugs should be called such drugs as "Pancreatin", "Pankurmen", "Pancytrat", "Festal", "Enzyme Forte" and others. In addition, bile is present in these medicines.
In some forms of chronic pancreatitis, complicated by pancreatic edema, such drugs as Gordox and Contrikal are prescribed. These medicines are administered to the patient intravenously (drip). One of the side effects that these drugs have for the pancreas is an allergic reaction. The risk of its occurrence during therapy is quite high. There is a high probability of anaphylactic shock. In this regard, anti-enzyme medications are prescribed with extreme caution.
Antispasmodics and analgesics
Analgesics are recommended to eliminate pain. These include, in particular, such drugs as “Analgin”, “Baralgin” and “Paracetamol”. At the very peak of the pathological condition, intramuscular injections are made to the patient. And after reducing the intensity of the patient's pain syndrome, they are transferred to the oral intake of these drugs. If the pain is not relieved, the doctor may prescribe narcotic analgesics. They not only have an analgesic effect, but also activate the effect of non-narcotic drugs. This category of drugs include tranquilizers, antidepressants, antipsychotics. These remedies, among other things, eliminate the anxious depressive state that often accompanies the pathologies of the pancreas. According to experts, the occurrence of pain is associated with dysfunction of the sphincter of Oddi, dyskinetic disorders of the intestine, accompanied by spasms. To eliminate such conditions, in parallel, apply appropriate medicines (means “No-shpa”, for example). Antispasmodics have an effect on muscle contractions, regardless of the nature of their origin.
If diseases of the pancreas occur accompanied with exocrine insufficiency on the basis of pain and dyspeptic syndrome, then during therapy they use drugs that suppress the excretion of hydrochloric acid by the stomach. This group of medicines is called antacids. Conventionally, these drugs for the pancreas are divided into two categories: absorbable and non-absorbable.
The first group should include magnesium oxide, sodium bicarbonate and others. The category of non-absorbable drugs includes such drugs for the pancreas as Fosfalyugel, Geusil, Almagel, and others. These drugs reduce the activity of the acid during its adsorption and the neutralization reaction proceeding slowly. Along with this, the number of enzymes destroyed in the stomach decreases. Antacid drugs for the treatment of the pancreas have an active neutralizing effect on hydrochloric acid. However, their influence is very short.
Is there a better remedy for the pancreas?
Experts do not give a clear answer to this question. Pathology of the organ in most cases suggest complex therapy. As mentioned above, the choice of drugs will depend on the clinical picture. However, taking enzymes as a replacement therapy for a long time is the most effective. However, as practice shows, it is not so often possible to achieve complete deliverance from pathology. Typically, these tools contribute to the normal activity of the pancreas. Some medications not only stabilize the secretion, but also prevent the occurrence of seizures, inflammation (such drugs include, for example, Enzyme Forte). However, it should be remembered that no prophylactic drugs (for the pancreas) will be useful if the diet is not being followed. Proper nutrition in the treatment of pancreatitis and other pathologies of the above-mentioned organ is of paramount importance.
Effective Pancreatic Medicines: CREON
This tool has an enzymatic effect, helps to improve the process of digestion. The active ingredient present in the composition of this medicine for the treatment of the pancreas, pakreatin, facilitates the digestion of fats, proteins, carbohydrates. This leads to their complete absorption. The drug is in capsule form. When ingested, the active release of hundreds of mini-microspheres begins. They are mixed with intestinal contents and normalize the distribution of enzymes. The release of active pancreatic enzymes of the drug occurs when the mini-microspheres of the small intestine is reached. Protease, amylase and lipase, which are part of pancreatin, have an effect that leads to the disintegration of lipid molecules, starch and fats.
Side effects and contraindications
The drug is not recommended for acute pancreatitis or exacerbation of its chronic form, hypersensitivity. As practice shows, the drug is tolerated very well by patients. Rare side effects include abdominal pain, vomiting or nausea, and a change in stool (diarrhea or constipation). In rare cases, patients experience an allergic reaction. As a rule, it is associated with hypersensitivity to the components of the tool.